ma:nyo Bifida Biome Complex Ampoule: expiry date and ingredients
How to read the expiry date printed on ma:nyo Bifida Biome Complex Ampoule, then what it is mostly made of and which ingredients do the work — based on the ingredient list the brand publishes.
Ingredient list from the US version (source checked 2026-10-29).
A fermentation-based ampoule with bifida ferments, multiple hyaluronic acids and squalane, said to hydrate and support the moisture barrier for plumper-looking skin.
Manufacture date and shelf life
Can I tell when my ma:nyo Bifida Biome Complex Ampoule was made from its batch code?
You do not need to. Korean cosmetics print the expiry date (or the manufacture date plus a period-after-opening) on the pack, for example EXP20270701 or MFD20240701.
How long does ma:nyo Bifida Biome Complex Ampoule last unopened?
ma:nyo does not publish an unopened shelf life we could verify (checked October 2026). Go by the date printed on the pack; Korean imports always carry one on the Korean label.
How long can I use it after opening?
Look for the open-jar symbol on the pack (for example 12M = 12 months after opening). Our period-after-opening calculator gives the exact date.
What it targets
Based on which ingredients are in it, how high up the list they are, and whether they are key actives.
Key ingredients
Probiotic-derived ferment marketed for barrier support.
Vitamin B3. Helps even out tone, supports the barrier and reduces the look of oiliness.
Ingredient guide →Anti-wrinkle ingredient approved for functional cosmetics in Korea (at 0.04%).
The salt form of hyaluronic acid; the version most products actually use.
Ingredient guide →Active compound from centella.
Ingredient guide →Copper peptide (GHK-Cu) studied for skin repair.
Ingredient guide →Worth knowing
Nothing in particular stood out.
What most of it is made of
- WaterBase
- Butylene GlycolHumectant
- Bifida Ferment LysateFerment
- GlycerinHumectant
- NiacinamideActive ingredient
We couldn’t find a marker ingredient (such as phenoxyethanol) to place the 1% line.
Full ingredient list, decoded (46)
| 1 | Water정제수The base of most creams and toners; dissolves the water-loving ingredients. | Base |
| 2 | Butylene Glycol부틸렌글라이콜Light humectant and solvent that helps other ingredients spread and absorb. | Humectant |
| 3 | Bifida Ferment Lysate비피다발효용해물Probiotic-derived ferment marketed for barrier support.Also in 6 of our products
| Ferment |
| 4 | Glycerin글리세린A classic humectant that draws water into the outer skin layer. Well tolerated by almost everyone. | Humectant |
| 5 | Niacinamide나이아신아마이드Vitamin B3. Helps even out tone, supports the barrier and reduces the look of oiliness.Ingredient guide → | Active ingredient |
| 6 | 1,2-Hexanediol1,2-헥산다이올Humectant that also helps preserve the formula; very common in Korean skincare. | Humectant |
| 7 | Pentylene Glycol펜틸렌글라이콜Humectant with mild antimicrobial action, used to cut down on classic preservatives. | Humectant |
| 8 | Squalane스쿠알란Stable, skin-like oil that softens without feeling heavy. | Emollient |
| 9 | Polyglyceryl-10 Laurate폴리글리세릴-10라우레이트Mild plant-derived emulsifier and solubiliser. | Emulsifier |
| 10 | Bifida Ferment Filtrate비피다발효여과물Ferment ingredient made with yeast or bacteria; used for conditioning.Also in 2 of our products | Ferment |
| 11 | Lactobacillus Ferment Lysate락토바실러스발효용해물Ferment ingredient made with yeast or bacteria; used for conditioning. | Ferment |
| 12 | Lactococcus Ferment Lysate락토코쿠스발효용해물Ferment ingredient made with yeast or bacteria; used for conditioning.Also in 2 of our products | Ferment |
| 13 | Saccharomyces Ferment Filtrate효모발효여과물Ferment ingredient made with yeast or bacteria; used for conditioning. | Ferment |
| 14 | Carbomer카보머Gelling agent that creates clear gels. | Thickener / texture |
| 15 | Hydrogenated Lecithin하이드로제네이티드레시틴Skin-friendly emulsifier that can also help actives penetrate. | Emulsifier |
| 16 | Tromethamine트로메타민pH adjuster. | pH adjuster |
| 17 | Xanthan Gum잔탄검Natural gum thickener.Also in 114 of our products | Thickener / texture |
| 18 | Propanediol프로판다이올Humectant and solvent, often plant-derived; also boosts preservation.Also in 95 of our products | Humectant |
| 19 | Ethylhexylglycerin에틸헥실글리세린Preservative booster, usually paired with phenoxyethanol. | Preservative |
| 20 | Adenosine아데노신Anti-wrinkle ingredient approved for functional cosmetics in Korea (at 0.04%). | Active ingredient |
| 21 | Dextrin덱스트린Thickener, film-former or powder that sets the texture and finish. | Thickener / texture |
| 22 | Theobroma Cacao Seed Extract카카오씨추출물Plant extract, usually present in small amounts for conditioning. | Plant extract |
| 23 | Sodium Hyaluronate소듐하이알루로네이트The salt form of hyaluronic acid; the version most products actually use.Ingredient guide →Also in 125 of our products | Humectant |
| 24 | Sodium Phytate소듐파이테이트Binds metal ions so the formula stays stable. | Chelating agent |
| 25 | Lactobacillus락토바실러스Ferment ingredient made with yeast or bacteria; used for conditioning. | Ferment |
| 26 | Cutibacterium Granulosum Ferment Extract Filtrate쿠티박테리움 그라눌로숨발효추출여과물Ferment ingredient made with yeast or bacteria; used for conditioning. | Ferment |
| 27 | Caffeine카페인Temporarily tightens and reduces puffiness, popular in eye creams.Also in 30 of our products | Active ingredient |
| 28 | Leontopodium Alpinum Callus Culture Extract에델바이스캘러스배양추출물Plant extract, usually present in small amounts for conditioning.Also in 2 of our products | Plant extract |
| 29 | Physalis Alkekengi Calyx Extract꽈리꽃받침추출물Plant extract, usually present in small amounts for conditioning.Also in 2 of our products | Plant extract |
| 30 | Hydrolyzed Algin하이드롤라이즈드알진Seaweed-derived humectant. | Humectant |
| 31 | Aureobasidium Pullulans Ferment흑효모발효물Ferment ingredient made with yeast or bacteria; used for conditioning.Also in 2 of our products | Ferment |
| 32 | Epigallocatechin Gallate에피갈로카테킨갈레이트Antioxidant that protects the formula from oxidation. | Antioxidant |
| 33 | Benzyl Glycol벤질글라이콜Solvent or carrier. | Solvent |
| 34 | Hydrolyzed Glycosaminoglycans하이드롤라이즈드글라이코사미노글리칸Humectant that helps skin hold on to water.Also in 1 of our products | Humectant |
| 35 | Asiaticoside아시아티코사이드Active compound from centella.Ingredient guide → | Soothing |
| 36 | Asiatic Acid아시아틱애씨드Centella compound used for soothing and repair.Ingredient guide → | Soothing |
| 37 | Madecassic Acid마데카식애씨드Centella asiatica compound, used for soothing and recovery.Ingredient guide → | Soothing |
| 38 | Hydroxypropyltrimonium Hyaluronate하이드록시프로필트라이모늄하이알루로네이트Modified hyaluronic acid that clings to skin for longer-lasting moisture.Ingredient guide → | Humectant |
| 39 | Sodium Hyaluronate Crosspolymer소듐하이알루로네이트크로스폴리머Cross-linked hyaluronic acid that forms a moisture-holding film.Ingredient guide →Also in 19 of our products | Humectant |
| 40 | Hydrolyzed Hyaluronic Acid하이드롤라이즈드하이알루로닉애씨드Smaller fragments of hyaluronic acid for lighter, layered hydration.Ingredient guide →Also in 18 of our products | Humectant |
| 41 | Sodium Acetylated Hyaluronate소듐아세틸레이티드하이알루로네이트Modified hyaluronic acid that binds to skin more strongly.Ingredient guide → | Humectant |
| 42 | Hyaluronic Acid하이알루로닉애씨드Holds many times its weight in water; plumps the surface layer with moisture.Ingredient guide → | Humectant |
| 43 | Copper Tripeptide-1카퍼트라이펩타이드-1Copper peptide (GHK-Cu) studied for skin repair.Ingredient guide →Also in 1 of our products | Active ingredient |
| 44 | Hydrolyzed Sodium Hyaluronate하이드롤라이즈드소듐하이알루로네이트Small fragments of hyaluronic acid for light, layered hydration.Ingredient guide → | Humectant |
| 45 | Acetyl Hexapeptide-8아세틸헥사펩타이드-8Peptide (Argireline) marketed to soften expression lines.Ingredient guide → | Active ingredient |
| 46 | Potassium Hyaluronate포타슘하이알루로네이트A salt form of hyaluronic acid that holds water in the skin’s surface.Ingredient guide → | Humectant |
Products with a similar ingredient list
- Isntree Hyaluronic Acid Watery Sun Gel SPF50+ PA++++Compare side by side →
- Anua Niacinamide 10% + TXA 4% SerumCompare side by side →
- BIODANCE Pore Perfecting Collagen Peptide SerumCompare side by side →
Shared ingredients only — this doesn’t mean the same effect or a substitute. Amounts and textures can differ. Very common ingredients (water, glycerin and the like) are not counted.
Based on the ingredient list the brand publishes; formulas can change and differ by country. The order shows relative amounts, not exact percentages. General information, not medical advice.
Ingredient list as published on the brand’s official website. Formulas change and can differ by country, so check the list on your pack too. General information, not medical advice.