Gluconolactone (PHA): what it does and how to use it

Gluconolactone is a polyhydroxy acid (PHA): a larger, slower exfoliant than AHAs that also hydrates, which makes it a common pick for sensitive skin.

What it does

• Loosens dead cells gradually for smoother texture.
• Draws in water like a humectant.
• Lactobionic acid is a related PHA with similar properties.

Strength and rules

• There is no specific legal limit for PHAs in the US or EU. Brands rarely state the percentage.

How to use it

• Can usually be used more often than AHAs.
• Wear sunscreen, as with any exfoliant.

Who should be careful

• Gentle does not mean zero irritation; patch test first if your skin reacts easily.

General information, not medical advice. If you have a skin condition or are pregnant, ask your doctor.